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Table 1 Estimated Na+ and H+ gradients across apical membrane of strial marginal cells

From: The gastric H,K-ATPase in stria vascularis contributes to pH regulation of cochlear endolymph but not to K secretion

 

[H+],e-b (nM)

[H+],c (nM)

[Na+],e-b (mM)

[Na+],c (mM)

RH (c/e-b)

RNa (e-b/c)

Direction of transport

In vitro

34 (pH 7.4)

63 (pH 7.2)

150

10

1.85

15

Na+ in

H+ out

In vivo

32 (pH 7.5)

63 (pH 7.2)

1

10

1.95

0.1

Na+ out

H+ in

  1. [H+], hydrogen ion concentration; [Na+], sodium ion concentration; e-b, endolymph (in vivo) or bath (in vitro); c, cytosol; RH RNa, Ratio of H+ and Na+ concentrations between compartments; Direction of transport into or out of the cell across the apical membrane of strial marginal cells