From: Myocardial susceptibility to ischaemia/reperfusion in obesity: a re-evaluation of the effects of age
Coronary flow (ml/min) | Aortic flow (ml/min) | Cardiac output (ml/min) | Heart rate (beats/min) | PSP (mm Hg) | Total Work (mW) | Total work (% recovery) | ||
---|---|---|---|---|---|---|---|---|
22 Weeks | ||||||||
Age-Matched Controls (6) | ||||||||
a6/6 | Before | 18.5 ± 0.9 | 46.1 ± 1.7 | 64.6 ± 2.2 | 282 ± 9 | 100 ± 2 | 14.40 ± 0.50 | |
After | 15.5 ± 1.4 | 23.1 ± 3.2 | 38.7 ± 4.1 | 277 ± 9 | 90 ± 2 | 7.81 ± 0.90 | 53.1 ± 4.8 | |
p | NS | 0.005 | 0.0001 | NS | 0.0001 | 0.0001 | ||
DIO (6) | ||||||||
a6/6 | Before | 19.1 ± 1.2 | 43.2 ± 1.3 | 62.3 ± 2.1 | 285 ± 9 | 99 ± 1 | 13.80 ± 0.47 | 69.4 ± 3.0+ |
After | 17.7 ± 0.8 | 28.4 ± 1.2 | 46.1 ± 1.5 | 272 ± 7 | 91 ± 1 | 9.38 ± 0.40 | ||
p | NS | 0.0001 | 0.0001 | NS | 0.001 | 0.0001 | ||
p1 | NS | NS | NS | NS | NS | NS | ||
17 months | ||||||||
Age-matched controls (6) | ||||||||
a5/6 | Before | 19.0 ± 3 | 48.0 ± 3.0 | 67.0 ± 3.6 | 274 ± 11 | 101 ± 2 | 14.91 ± 0.9 | |
After | 19.0 ± 1 | 29.7 ± 8.1 | 48.7 ± 8.7 | 223 ± 47 | 80 ± 16 | 9.72 ± 2.47 | 66.8 ± 16.7 | |
p | NS | 0.041 | NS | NS | NS | NS | ||
p2 | NS | NS | NS | NS | NS | NS | NS | |
DIO (6) | ||||||||
a3/6 | Before | 21.7 ± 1.7 | 36.3 ± 6.5 | 58.0 ± 6.5 | 258 ± 8 | 99 ± 2.5 | 12.84 ± 1.71 | |
After | 21.3 ± 1.7 | 18.0 ± 9.3 | 39.3 ± 9.4 | 107 ± 53 | 47 ± 21 | 6.21 ± 3.0 | 43.6 ± 20.1 | |
p | NS | NS | NS | 0.026 | NS | NS | NS | |
p1 | NS | NS | NS | 0.05 | NS | NS | NS | |
p3 | 0.049 | NS | NS | 0.001 | 0.0172 | NS | NS |