Table 2 Effects of intravesical disulfide and all-thiol HMGB1 on mouse bladder histology
From: Disulfide high mobility group box-1 causes bladder pain through bladder Toll-like receptor 4
| Â | Inflammation | Edema | ||
|---|---|---|---|---|
Dose (μg) | ds HMGB1 | all-thiol HMGB1 | ds HMGB1 | all-thiol HMGB1 |
0 | 0 | 0 | 0 | 0 |
1 | 0 | 0 | 0.4 ± 0.2 | 1.3 ± 0.7 |
2 | 0 | 0 | 0.7 ± 0.7 | 0.7 ± 0.3 |
5 | 0 | 0 | 0 | 1.0 ± 0.6 |
10 | 0 | 0 | 0.2 ± 0.2 | 0.9 ± 0.5 |
20 | 0.3 ± 0.3 | 0.3 ± 0.3 | 1.0 ± 1.0 | 0.7 ± 0.7 |