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Table 2 Effects of intravesical disulfide and all-thiol HMGB1 on mouse bladder histology

From: Disulfide high mobility group box-1 causes bladder pain through bladder Toll-like receptor 4

  Inflammation Edema
Dose (μg) ds HMGB1 all-thiol HMGB1 ds HMGB1 all-thiol HMGB1
0 0 0 0 0
1 0 0 0.4 ± 0.2 1.3 ± 0.7
2 0 0 0.7 ± 0.7 0.7 ± 0.3
5 0 0 0 1.0 ± 0.6
10 0 0 0.2 ± 0.2 0.9 ± 0.5
20 0.3 ± 0.3 0.3 ± 0.3 1.0 ± 1.0 0.7 ± 0.7
  1. 0 = vehicle control