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Fig. 1 | BMC Physiology

Fig. 1

From: Deficiency of the BMP Type I receptor ALK3 partly protects mice from anemia of inflammation

Fig. 1

Milder Anaemia of inflammation in Alk3fl/fl; Alb-Cre mice compared to Alk3fl/fl mice. a Haemoglobin values from Alk3fl/fl and Alk3fl/fl; Alb-Cre mice 14 days after heat-killed Brucella abortus (BA) or saline injection (*P = 0.01: Alk3fl/fl injected with saline [n = 4] vs Alk3fl/fl injected with BA [n = 6]; *P = 0.01: Alk3fl/fl; Alb-Cre injected with saline [n = 4] vs Alk3fl/fl; Alb-Cre injected with BA [n = 6]; *P = 0.04: Alk3fl/fl injected with BA [n = 6] vs Alk3fl/fl; Alb-Cre injected with BA [n = 6]). b Reticulocyte Production Index (*P = 0.03: Alk3fl/fl injected with saline vs Alk3fl/fl injected with BA; *P = 0.01: Alk3fl/fl; Alb-Cre injected with saline vs Alk3fl/fl; Alb-Cre injected with BA). c Serum iron from Alk3fl/fl and Alk3fl/fl; Alb-Cre mice 14 days after BA administration (**P = 0.004: Alk3fl/fl injected with BA vs Alk3fl/fl; Alb-Cre injected with BA). d Transferrin saturation (**P = 0.01: Alk3fl/fl injected with BA vs Alk3fl/fl; Alb-Cre injected with BA [n = 5])

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