Figure 1

A. Developed pressure at perfusate calcium 1.5 – 3.5 mM and with dobutamine (dob, 0.9 μM). B. Peak systolic intracellular calcium, C. Myocardial oxygen consumption (MVO₂), D. Ratio of developed pressure to myocardial oxygen consumption (DP/ MVO₂). Symbols for Figure 1A: ^* p < 0.005 vs perfusate calcium 2.0, 2.5, 3.5 mM and dobutamine; † p < 0.05 vs dobutamine and perfusate calcium 3.5 mM; §p < 0.0001 vs dobutamine; ^** p < 0.05 vs dobutamine; Symbols for Figure 1B:^* p < 0.005 vs perfusate calcium 3.5 mM and dobutamine; † p < 0.05 vs perfusate calcium 3.5 mM and dobutamine; Symbols for Figure 1C:^† p = 0.05 vs dobutamine; ^§ p < 0.05 vs dobutamineSymbols for Figure 1D:^* p < 0.0001 vs perfusate calcium 2.0, 2.5, 3.5 mM and dobutamine; † p < 0.0001 vs dobutamine; §p < 0.0005 vs dobutamine; ^** p < 0.05 vs dobutamine