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  1. Content type: Research article

    Inflammatory stimuli induce the hepatic iron regulatory hormone hepcidin, which contributes to anaemia of inflammation (AI). Hepcidin expression is regulated by the bone morphogenetic protein (BMP) and the int...

    Authors: Inka Gallitz, Niklas Lofruthe, Lisa Traeger, Nicole Bäumer, Verena Hoerr, Cornelius Faber, Tanja Kuhlmann, Carsten Müller-Tidow and Andrea U. Steinbicker

    Citation: BMC Physiology 2018 18:3

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  2. Content type: Research article

    Circadian rhythms of physiology and behavior are driven by a circadian clock located in the suprachiasmatic nucleus of the hypothalamus. This clock is synchronized to environmental day/night cycles by photic i...

    Authors: Jessica A. Krizo, Linley E. Moreland, Ashutosh Rastogi, Xiang Mou, Rebecca A. Prosser and Eric M. Mintz

    Citation: BMC Physiology 2018 18:2

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  3. Content type: Research article

    Thermogenic impairment promotes obesity and insulin resistance. Adiponectin is an important regulator of energy homeostasis. While many beneficial metabolic effects of adiponectin resemble that of activated th...

    Authors: Qiong Wei, Jong Han Lee, Hongying Wang, Odelia Y. N. Bongmba, Chia-Shan Wu, Geetali Pradhan, Zilin Sun, Lindsey Chew, Mandeep Bajaj, Lawrence Chan, Robert S. Chapkin, Miao-Hsueh Chen and Yuxiang Sun

    Citation: BMC Physiology 2017 17:8

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  4. Content type: Research article

    Previous studies show that androgens are involved in hypertrophy and excitability of cardiomyocytes and that their effects are mediated through their receptor. The aim of this study was to evaluate the presenc...

    Authors: Enrique Pedernera, María José Gómora, Iván Meneses, Marlon De Ita and Carmen Méndez

    Citation: BMC Physiology 2017 17:7

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  5. Content type: Research article

    Bladder pain is a prominent symptom in several urological conditions (e.g. infection, painful bladder syndrome/interstitial cystitis, cancer). Understanding the mechanism of bladder pain is important, particul...

    Authors: Fei Ma, Dimitrios E. Kouzoukas, Katherine L. Meyer-Siegler, Karin N. Westlund, David E. Hunt and Pedro L. Vera

    Citation: BMC Physiology 2017 17:6

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  6. Content type: Methodology article

    Obese individuals differ in their risk of developing metabolic and cardiovascular complications depending on fat distribution (subcutaneous versus visceral) and adipose tissue (AT) phenotype (hyperplasic versu...

    Authors: Kathrin Landgraf, Susanne Schuster, Andrej Meusel, Antje Garten, Thomas Riemer, Dorit Schleinitz, Wieland Kiess and Antje Körner

    Citation: BMC Physiology 2017 17:4

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  7. Content type: Research article

    Reports on the effect of age and obesity on myocardial ischaemia/reperfusion (I/R) injury and ischaemic preconditioning are contradictory. The aim of this study was to re-evaluate the effects of age and diet-i...

    Authors: I. Webster, R. Salie, E. Marais, W.-J. Fan, G. Maarman, B. Huisamen and A. Lochner

    Citation: BMC Physiology 2017 17:3

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  8. Content type: Research article

    In preparation for migration from freshwater to marine habitats, Atlantic salmon (Salmo salar L.) undergo smoltification, a transformation that includes the acquisition of hyposmoregulatory capacity. The growth h...

    Authors: Jason P. Breves, Chelsea K. Fujimoto, Silas K. Phipps-Costin, Ingibjörg E. Einarsdottir, Björn Thrandur Björnsson and Stephen D. McCormick

    Citation: BMC Physiology 2017 17:2

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  9. Content type: Research article

    In many vascular smooth muscle cells (SMCs), ryanodine receptor-mediated Ca2+ sparks activate large-conductance Ca2+-activated K+ (BK) channels leading to lowered SMC [Ca2+]i and vasodilation. Here we investigate...

    Authors: Gayathri Krishnamoorthy, Katrin Reimann and Philine Wangemann

    Citation: BMC Physiology 2016 16:6

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  10. Content type: Research article

    Trimester-specific reference ranges for T3, T4, and TSH need to be established in different communities. Neither Sudan nor other African countries have established trimester-specific reference ranges for TSH, ...

    Authors: Enaam T. Elhaj, Ishag Adam, Mohamed A. Ahmed and Mohamed F. Lutfi

    Citation: BMC Physiology 2016 16:5

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  11. Content type: Research article

    Disturbance of acid–base balance in the inner ear is known to be associated with hearing loss in a number of conditions including genetic mutations and pharmacologic interventions. Several previous physiologic...

    Authors: Hiromitsu Miyazaki, Philine Wangemann and Daniel C. Marcus

    Citation: BMC Physiology 2016 17:1

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  12. Content type: Research article

    In vitro isolated heart preparations are valuable tools for the study of cardiac anatomy and physiology, as well as for preclinical device testing. Such preparations afford investigators a high level of hemody...

    Authors: Ryan P. Goff, Brian T. Howard, Stephen G. Quallich, Tinen L. Iles and Paul A. Iaizzo

    Citation: BMC Physiology 2016 16:4

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  13. Content type: Research article

    The cell type, cell status and specific localization of Prothymosin α (PTMA) within cells seemingly determine its function. PTMA undergoes 2 types of protease proteolytic modifications that are useful in eluci...

    Authors: Caroline Mwendwa Kijogi, Christopher Khayeka-Wandabwa, Keita Sasaki, Yoshimasa Tanaka, Hiroshi Kurosu, Hayato Matsunaga and Hiroshi Ueda

    Citation: BMC Physiology 2016 16:2

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  14. Content type: Research article

    Veterinary cardiology, especially electrocardiography, has shown major advancements for all animal species. Consequently, the number of ovine species used as experimental animals has increased to date. Few stu...

    Authors: Karoline Koether, Carla Maria Vela Ulian, Maria Lucia Gomes Lourenço, Renato Souza Gonçalves, Mateus José Sudano, Raíssa Karolliny Salgueiro Cruz, Naiana da Silva Branchini, Angélica Alfonso and Simone Biagio Chiacchio

    Citation: BMC Physiology 2016 16:1

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  15. Content type: Methodology article

    Iodine-based solutions have long been known to be effective in aiding the differentiation among soft tissues in both fundamental anatomical research and for clinical diagnoses. Recently the combination of this...

    Authors: Zhiheng Li, Julia A. Clarke, Richard A. Ketcham, Matthew W. Colbert and Fei Yan

    Citation: BMC Physiology 2015 15:5

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  16. Content type: Research article

    Neurogenic pulmonary edema (NPE) is a non-cardiogenic form of pulmonary edema that can occur consequent to central neurologic insults including stroke, traumatic brain injury, and seizure. NPE is a public heal...

    Authors: Shadi Khademi, Melinda A. Frye, Kimberly M. Jeckel, Thies Schroeder, Eric Monnet, Dave C. Irwin, Patricia A. Cole, Christopher Bell, Benjamin F. Miller and Karyn L. Hamilton

    Citation: BMC Physiology 2015 15:4

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  17. Content type: Research article

    There is increasing evidence that poor growth of preterm infants is a risk factor for poor long-term development, while the effects of early postnatal growth restriction are not well known. We utilized a rat m...

    Authors: Erica E. Alexeev, Bo Lönnerdal and Ian J. Griffin

    Citation: BMC Physiology 2015 15:3

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  18. Content type: Research article

    Elevated blood pressure is an important global health problem, and in-utero under-nutrition may be an important factor in the pathogenesis of hypertension. In the present study, we tested the hypothesis that ante...

    Authors: Ravi Goyal, Jonathan Van-Wickle, Dipali Goyal and Lawrence D. Longo

    Citation: BMC Physiology 2015 15:2

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  19. Content type: Research article

    Exercise is a non-pharmacologic agent widely used for hypertension control, where low intensity is often associated with blood pressure reduction. Maximal lactate steady state (MLSS) was recently identified in...

    Authors: Bernardo A Petriz, Jeeser A Almeida, Clarissa P C Gomes, Carlos Ernesto, Rinaldo W Pereira and Octavio L Franco

    Citation: BMC Physiology 2015 15:1

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  20. Content type: Research article

    Heat illness is a debilitating and potentially life-threatening condition. Limited data are available to identify individuals with heat illness at greatest risk for organ damage. We recently described the tran...

    Authors: Danielle L Ippolito, John A Lewis, Chenggang Yu, Lisa R Leon and Jonathan D Stallings

    Citation: BMC Physiology 2014 14:14

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  21. Content type: Research article

    The multi-meric calcium/calmodulin-dependent protein kinase II (CaMKII) is the main CaMK in skeletal muscle and its expression increases with endurance training. CaMK family members are implicated in contracti...

    Authors: Wouter Eilers, Richard T Jaspers, Arnold de Haan, Céline Ferrié, Paola Valdivieso and Martin Flück

    Citation: BMC Physiology 2014 14:7

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