Warren JW, Brown V, Jacobs S, Horne L, Langenberg P, Greenberg P. Urinary tract infection and inflammation at onset of interstitial cystitis/painful bladder syndrome. Urology. 2008;71(6):1085–90.
Article
PubMed
Google Scholar
Westropp JL, Buffington CA. In vivo models of interstitial cystitis. J Urol. 2002;167(2 Pt 1):694–702.
Article
PubMed
Google Scholar
Olivar T, Laird JM. Cyclophosphamide cystitis in mice: behavioural characterisation and correlation with bladder inflammation. Eur J Pain. 1999;3(2):141–9.
Article
CAS
PubMed
Google Scholar
Vera PL, Iczkowski KA, Howard DJ, Jiang L, Meyer-Siegler KL. Antagonism of macrophage migration inhibitory factor decreases cyclophosphamide cystitis in mice. Neurourol Urodyn. 2010;29(8):1451–7.
Article
CAS
PubMed
Google Scholar
Tanaka J, Yamaguchi K, Ishikura H, Tsubota M, Sekiguchi F, Seki Y, Tsujiuchi T, Murai A, Umemura T, Kawabata A. Bladder pain relief by HMGB1 neutralization and soluble thrombomodulin in mice with cyclophosphamide-induced cystitis. Neuropharmacology. 2014;79:112–8.
Article
CAS
PubMed
Google Scholar
Kato J, Svensson CI. Role of extracellular damage-associated molecular pattern molecules (DAMPs) as mediators of persistent pain. Prog Mol Biol Transl Sci. 2015;131:251–79.
Article
PubMed
Google Scholar
Agalave NM, Svensson CI. Extracellular high-mobility group box 1 protein (HMGB1) as a mediator of persistent pain. Mol Med. 2014;20:569–78.
Google Scholar
Nakamura Y, Morioka N, Abe H, Zhang FF, Hisaoka-Nakashima K, Liu K, Nishibori M, Nakata Y. Neuropathic pain in rats with a partial sciatic nerve ligation is alleviated by intravenous injection of monoclonal antibody to high mobility group box-1. PLoS One. 2013;8(8):e73640.
Article
CAS
PubMed
PubMed Central
Google Scholar
Kouzoukas DE, Meyer-Siegler KL, Ma F, Westlund KN, Hunt DE, Vera PL. Macrophage Migration Inhibitory Factor Mediates PAR-Induced Bladder Pain. PLoS One. 2015;10(5):e0127628.
Article
PubMed
PubMed Central
Google Scholar
Kouzoukas DE, Ma F, Meyer-Siegler KL, Westlund KN, Hunt DE, Vera PL. Protease-activated receptor 4 induces bladder pain through high mobility group box-1. PLoS One. 2016;11(3):e0152055.
Article
PubMed
PubMed Central
Google Scholar
Belcher JD, Chen C, Nguyen J, Milbauer L, Abdulla F, Alayash AI, Smith A, Nath KA, Hebbel RP, Vercellotti GM. Heme triggers TLR4 signaling leading to endothelial cell activation and vaso-occlusion in murine sickle cell disease. Blood. 2014;123(3):377–90.
Article
CAS
PubMed
PubMed Central
Google Scholar
Deane R, Singh I, Sagare AP, Bell RD, Ross NT, LaRue B, Love R, Perry S, Paquette N, Deane RJ, et al. A multimodal RAGE-specific inhibitor reduces amyloid beta-mediated brain disorder in a mouse model of Alzheimer disease. J Clin Invest. 2012;122(4):1377–92.
Article
CAS
PubMed
PubMed Central
Google Scholar
Sugino Y, Kanematsu A, Hayashi Y, Haga H, Yoshimura N, Yoshimura K, Ogawa O. Voided stain on paper method for analysis of mouse urination. Neurourol Urodyn. 2008;27(6):548–52.
Article
CAS
PubMed
Google Scholar
Cousineau D. Confidence intervals in within-subject designs: A simpler solution to Loftus and Masson's method. Tutorials in Quantitative Methods for Psychology. 2005;1(1):42–5.
Article
Google Scholar
Core Team: R: A Language and Environment for Statistical Computing. R Foundation for Statistical Computing 1993.
Sui G, Fry CH, Montgomery B, Roberts M, Wu R, Wu C. Purinergic and muscarinic modulation of ATP release from the urothelium and its paracrine actions. Am J Physiol Renal Physiol. 2014;306(3):F286–98.
Article
CAS
PubMed
Google Scholar
Shiina K, Hayashida KI, Ishikawa K, Kawatani M. ATP release from bladder urothelium and serosa in a rat model of partial bladder outlet obstruction. Biomed Res. 2016;37(5):299–304.
Article
CAS
PubMed
Google Scholar
Coelho A, Wolf-Johnston AS, Shinde S, Cruz CD, Cruz F, Avelino A, Birder LA. Urinary bladder inflammation induces changes in urothelial nerve growth factor and TRPV1 channels. Br J Pharmacol. 2015;172(7):1691–9.
Article
CAS
PubMed
PubMed Central
Google Scholar
Gonzalez EJ, Merrill L, Vizzard MA. Bladder sensory physiology: neuroactive compounds and receptors, sensory transducers, and target-derived growth factors as targets to improve function. Am J Physiol Regul Integr Comp Physiol. 2014;306(12):R869–78.
Article
CAS
PubMed
PubMed Central
Google Scholar
Tanaka J, Seki Y, Ishikura H, Tsubota M, Sekiguchi F, Yamaguchi K, Murai A, Umemura T, Kawabata A. Recombinant human soluble thrombomodulin prevents peripheral HMGB1-dependent hyperalgesia in rats. Br J Pharmacol. 2013;170(6):1233–41.
Article
CAS
PubMed
PubMed Central
Google Scholar
Shibasaki M, Sasaki M, Miura M, Mizukoshi K, Ueno H, Hashimoto S, Tanaka Y, Amaya F. Induction of high mobility group box-1 in dorsal root ganglion contributes to pain hypersensitivity after peripheral nerve injury. Pain. 2010;149(3):514–21.
Article
CAS
PubMed
Google Scholar
Feldman P, Due MR, Ripsch MS, Khanna R, White FA. The persistent release of HMGB1 contributes to tactile hyperalgesia in a rodent model of neuropathic pain. J Neuroinflammation. 2012;9:180.
Article
CAS
PubMed
PubMed Central
Google Scholar
Agalave NM, Larsson M, Abdelmoaty S, Su J, Baharpoor A, Lundback P, Palmblad K, Andersson U, Harris H, Svensson CI. Spinal HMGB1 induces TLR4-mediated long-lasting hypersensitivity and glial activation and regulates pain-like behavior in experimental arthritis. Pain. 2014;155(9):1802–13.
Article
CAS
PubMed
Google Scholar
Li X, Yang H, Ouyang Q, Liu F, Li J, Xiang Z, Yuan H. Enhanced RAGE expression in the dorsal root ganglion may contribute to neuropathic pain induced by spinal nerve ligation in rats. Pain Med. 2016;17(5):803–12.
PubMed
Google Scholar
Ma YQ, Chen YR, Leng YF, Wu ZW. Tanshinone IIA downregulates HMGB1 and TLR4 expression in a spinal nerve ligation model of neuropathic pain. Evidence-based complementary and alternative medicine : eCAM. 2014;2014:639563.
Google Scholar
Roundy LM, Jia W, Zhang J, Ye X, Prestwich GD, Oottamasathien S. LL-37 induced cystitis and the receptor for advanced glycation end-products (RAGE) pathway. Adv Biosci Biotechnol. 2013;4(8B):1–8.
Article
PubMed
PubMed Central
Google Scholar
Yamasoba D, Tsubota M, Domoto R, Sekiguchi F, Nishikawa H, Liu K, Nishibori M, Ishikura H, Yamamoto T, Taga A, et al. Peripheral HMGB1-induced hyperalgesia in mice: Redox state-dependent distinct roles of RAGE and TLR4. J Pharmacol Sci. 2016;130(2):139–42.
Article
CAS
PubMed
Google Scholar
Wang YS, Li YY, Wang LH, Kang Y, Zhang J, Liu ZQ, Wang K, Kaye AD, Chen L. Tanshinone IIA attenuates chronic pancreatitis-induced pain in rats via downregulation of HMGB1 and TRL4 expression in the spinal cord. Pain Physician. 2015;18(4):E615–28.
PubMed
Google Scholar
Allette YM, Due MR, Wilson SM, Feldman P, Ripsch MS, Khanna R, White FA. Identification of a functional interaction of HMGB1 with receptor for advanced glycation End-products in a model of neuropathic pain. Brain Behav Immun. 2014;42:169–77.
Article
CAS
PubMed
PubMed Central
Google Scholar
Hua F, Tang H, Wang J, Prunty MC, Hua X, Sayeed I, Stein DG. TAK-242, an antagonist for Toll-like receptor 4, protects against acute cerebral ischemia/reperfusion injury in mice. J Cereb Blood Flow Metab. 2015;35(4):536–42.
Article
CAS
PubMed
PubMed Central
Google Scholar
Song J, Bishop BL, Li G, Duncan MJ, Abraham SN. TLR4-initiated and cAMP-mediated abrogation of bacterial invasion of the bladder. Cell Host Microbe. 2007;1(4):287–98.
Article
CAS
PubMed
PubMed Central
Google Scholar
Due MR, Piekarz AD, Wilson N, Feldman P, Ripsch MS, Chavez S, Yin H, Khanna R, White FA. Neuroexcitatory effects of morphine-3-glucuronide are dependent on Toll-like receptor 4 signaling. J Neuroinflammation. 2012;9:200.
Article
CAS
PubMed
PubMed Central
Google Scholar
Kim HJ. Update on the pathology and diagnosis of interstitial cystitis/bladder pain syndrome: a review. Int Neurourol J. 2016;20(1):13–7.
Article
PubMed
PubMed Central
Google Scholar
Fry CH, Vahabi B. The role of the mucosa in normal and abnormal bladder function. Basic Clin Pharmacol Toxicol. 2016;119 Suppl 3:57–62.
Article
CAS
PubMed
Google Scholar
Boucher W, el-Mansoury M, Pang X, Sant GR, Theoharides TC. Elevated mast cell tryptase in the urine of patients with interstitial cystitis. Br J Urol. 1995;76(1):94–100.
Article
CAS
PubMed
Google Scholar
Kuromitsu S, Yokota H, Hiramoto M, Morita S, Mita H, Yamada T. Increased concentration of neutrophil elastase in urine from patients with interstitial cystitis. Scand J Urol Nephrol. 2008;42(5):455–61.
Article
CAS
PubMed
Google Scholar