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Table 1 Effects of intravesical disulfide and all-thiol HMGB1 on mouse micturition

From: Disulfide high mobility group box-1 causes bladder pain through bladder Toll-like receptor 4

  ds HMGB1 all-thiol HMGB1
Dose (μg) Volume (μl) Freq Volume (μl) Freq
0 301 ± 39.3 3.0 ± 0.4 301 ± 39.3 3.0 ± 0.4
1 288 ± 20.1 3.5 ± 0.6 230 ± 9.2 4.3 ± 0.7
2 359 ± 13.9 2.0 ± 0.0 240 ± 79.8 5.3 ± 1.7
5 255 ± 36.8 3.2 ± 0.9 267 ± 35.0 4.3 ± 0.9
10 264 ± 25.5 4.1 ± 1.0 214 ± 15.8 4.0 ± 0.8
20 141 ± 7.3* 7.3 ± 0.7* 177 ± 23.7* 4.7 ± 0.3*
  1. 0 = vehicle control
  2. *p < 0.05 compared with 0 μg disulfide HMGB1