Table 2 EC50-values (concentration for half-maximal effect) of CCh for contractile and electrophysiological parameters of the crucian carp sinoatrial tissue and atrial cardiomyocytes
Parameter | 4°C acclimated fish EC50 | 18°C acclimated fish EC50 | Statistically significant differences (p < 0.05) between mean EC50 values with the listed parameters |
|---|---|---|---|
HR | 2.02e-7 ± 0.2 | 1.23e-7 ± 0.03 | Fmax, IK |
Fmax | 3.50e-8 ± 0.03 | 2.75e-8 ± 0.1 | HR, DC, IK |
DC | 1.11e-7 ± 0.1 | 1.46e-7 ± 0.1 | Fmax, IK |
IK, CCh at 4°C/18°C | 4.47e-6 ± 0.2 | 3.47e-6 ± 0.7 | HR, Fmax, DC |