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Figure 1 | BMC Physiology

Figure 1

From: Different stress-related phenotypes of BALB/c mice from in-house or vendor: alterations of the sympathetic and HPA axis responsiveness

Figure 1

Differences of stress responses of in-house-bred and vendor-derived, shipped mice. A, B. Plasma corticosterone levels (A; ANOVA: F = 9.169; p < 0.001) and blood lymphocyte counts (B; ANOVA: F = 70.87; p < 0.001) of acutely stressed (black bars) and non-stressed mice (white bars) four weeks after room change (in-house bred) or shipment from vendor; n = 12 mice/group; summary of two independent experiments giving similar results. C. ACTH-induced (grey bars) and BSA control treatment-induced (white bars) plasma corticosterone levels measured four weeks after shipment from vendor or room change of in-house bred mice (ANOVA: F = 80.15; p < 0.001); n = 2 experiments; n = 6 mice/group; *p < 0.05, **p < 0.01, ***p < 0.001 compared with in-house bred, acutely stressed or ACTH-challenged group; ###p < 0.001 compared with in-house bred, non-stressed group; ††p < 0.01 compared with vendor-derived control group; comparison by Tukey test.

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BMC Physiology

ISSN: 1472-6793

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