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Figure 4 | BMC Physiology

Figure 4

From: Different stress-related phenotypes of BALB/c mice from in-house or vendor: alterations of the sympathetic and HPA axis responsiveness

Figure 4

Different acute stress response with or without reserpine treatment of in-house bred and vendor-derived mice. Plasma corticosterone levels (A, ANOVA: F = 8.275, p = 0.0002) and lymphocyte counts of in-house bred (B, ANOVA: F = 114.6, p < 0.0001) as well as corticosterone levels (C, ANOVA: F(4) = 13.39, p < 0.0001) and lymphocyte counts in the blood of vendor-derived, shipped mice (D, ANOVA: F(4) = 42.48, p < 0.0001) immediately after acute stress exposure (black bars) compared with non-stressed animals (white bars). Mice were either pre-treated with reserpine in order to block sympathetic output during stress or control-treated with NaCl. n = 12 mice/group representative for two experiments giving similar results; *p < 0.05, **p < 0.01, ***p < 0.001 compared with NaCl treated, non-stressed mice, ###p < 0.001 compared with reserpine treated, non-stressed mice, †††compared with NaCl treated, acutely stressed mice; comparison by Tukeys' test.

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BMC Physiology

ISSN: 1472-6793

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