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Figure 7 | BMC Physiology

Figure 7

From: Up-regulation of avian uncoupling protein in cold-acclimated and hyperthyroid ducklings prevents reactive oxygen species production by skeletal muscle mitochondria

Figure 7

Relationship between the fraction of O 2 turned into H 2 O 2 instead of being reduced to water (free radical leak) and the UCP-dependent mitochondrial proton leak in mitochondria extracted from thermoneutral controls (open square), cold-acclimated (black cycle), hypothyroid (open diamond) or T 3 -treated ducklings (black triangle). UCP-dependent proton leak was calculated from the difference between XXO-activated and GDP-sensitive respiration at 170 mV, assuming a stoichiometry of 6. There was a linear relationship between both parameters (y = -0.019x + 5.567, R2 = 0.92). Values are means ± S.E.M.

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