Figure 1

Mouse bladder inflammation. Representative photomicrographs from the urinary bladders isolated from mice chronically treated with 4 weekly instillations of PBS (A), BCG (B), VEGF₁₆₅ (C), and VEGF₁₂₁ (D). Black box inserts on B, C, and D correspond to a 200% magnification of the original dashed box area of the respective figures and illustrate inflammatory cells. White transversal bars indicate the urothelium, yellow bars indicate the sub-urothelium, and green bars indicate the detrusor smooth muscle. Green arrow indicates perivascular infiltrate of inflammatory cells (D). See Figures 2 and 3 for quantification of inflammatory cells by image analysis.