Figure 13

VEGF triggered an enhanced abdominal sensitivity in response to mechanical stimulation with von Frey filaments. Effects of intravesical VEGF on the development of viscerosomatic hyperalgesia as measured by the response to mechanical stimulation of the lower abdominal area using von Frey filaments. * - p≤0.05 when compared to the control group. This data suggests that intravesical VEGF induced the development of abdominal hypersensitivity in pelvic area which could be a reflection of abdominal discomfort/pain.