Figure 3From: Genomic homeostasis is dysregulated in favour of apoptosis in the colonic epithelium of the azoxymethane treated ratBox plots demonstrating gene expression (microarray dataset) six hours after AOM treatment in the proximal and distal colonic epithelium for the genes: H2AFX (H2A histone family member X), MGMT (O-6-methylguanine DNA methyltransferase), Xrcc4 (X-ray repair complementing defective repair in Chinese hamster cells 4), MSH3 (mutS homolog 3 (E. coli)), Apex1 (apurinic/apyrimidinic endonuclease 1), Pol β (polymerase, DNA directed beta), MBD1 (methyl-CpG binding domain protein 1), MDM2 (p53 E3 ubiquitin protein ligase homolog), OGG1 (8-oxoguanine DNA glycosylase).Back to article page