Table 2 Baseline characteristics of renovascular-hypertension models (2-kidney-1-clip, 1-kidney-1-clip), and of normal controls following sham-surgery

Heart rate (bpm)

455.3 ± 60.8

472.5 ± 54.9

463.6 ± 55.4

ns

Systolic blood pressure - baseline (mmHg)

100.9 ± 5.5

144.8 ± 13.0

152.3 ± 16.6

<0.0001

Diastolic blood pressure - baseline (mmHg)

76.7 ± 4.3

106.4 ± 12.7

109.2 ± 8.7

0.0001

Heart rate – after atropine (bpm)

559.8 ± 58.1

575.9 ± 82.5

604.4 ± 55.4

ns

Systolic blood pressure - after atropine (mmHg)

108.9 ± 6.6

152.7 ± 16.1

151.2 ± 15.3

<0.0001

Diastolic blood pressure - after atropine (mmHg)

85.9 ± 6.0

116.0 ± 11.9

111.2 ± 8.4

<0.0001

Heart rate – after metoprolol (bpm)

463.0 ± 74.0

513.8 ± 67.6

479.3 ± 49.4

ns

Systolic blood pressure - after metoprolol (mmHg)

100.2 ± 10.8

155.1 ± 14.9

151.1 ± 15.3

<0.0001

Diastolic blood pressure - after metoprolol (mmHg)

77.3 ± 9.2

114.1 ± 13.4

111.4 ± 10.5

<0.0001