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Table 1 Anaphylaxis induced vascular permeability. Effects of feG and dexamathasone (Dex) on vascular permeability changes induced by oral challenge with OA (100 mg/kg). The animals were treated with feG or Dex at 30 min or 12 h before antigen challenge.

From: The tripeptide feG ameliorates systemic inflammatory responses to rat intestinal anaphylaxis

 

No Antigen

Antigen

Tissue

Control

Saline

feG -30 min

Dex-30 min

feG -12 h

Dex -12 h

Pinna

2.4 ± 0.2a

3.2 ± 0.2*

2.1 ± 0.5#

3.3 ± 0.4*

2.9 ± 0.3

2.2 ± 0.3#

Jejunum

16.6 ± 0.9

32.2 ± 4.3*

15.8 ± 0.8#

ND

20.5 ± 2.3

17.6 ± 2.8#

Ileum

19.0 ± 1.4

27.8 ± 3.4*

16.3 ± 1.3#

22.8 ± 0.8

23.7 ± 1.9

17.2 ± 2.3#

  1. a = Values presented as mean ± SEM. N values = 4. Significance: P < 0.05; * greater than Control; # less than Saline (antigen only).
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BMC Physiology

ISSN: 1472-6793

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