Figure 2
From: Monitoring immediate-early gene expression through firefly luciferase imaging of HRS/J hairless mice
Expression in similar body regions of overdosed CMV::luc and fos::luc mice. (A) CMV::luc neonate showing higher expression than (B) a fos::luc neonate. Both had highest expression in the paws, tail, ears, and nose, but the CMV::luc mice also showed a bright signal from a point on the dorsal surface of the head. Likewise, adult CMV::luc (C) and fos::luc mice (D) had similar gene expression patterns, like those of neonates, with a few exceptions. CMV::luc adults also showed expression through the eyes and fur of the abdomen (short arrows). (Paws: long arrows.) Adult signals are shown as pseudocolor overlays on the reference whole-animal images. Bioluminescence intensity is presented in analog-to-digital units (ADUs) of the camera according to scale at left of each image in all figures.