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  1. A large body of evidence shows that a single bout of strenuous exercise induces oxidative stress in circulating human lymphocytes leading to lipid peroxidation, DNA damage, mitochondrial perturbations, and pro...

    Authors: Gabriella Marfe, Marco Tafani, Bruna Pucci, Carla Di Stefano, Manuela Indelicato, Angela Andreoli, Matteo Antonio Russo, Paola Sinibaldi-Salimei and Vincenzo Manzi
    Citation: BMC Physiology 2010 10:7
    Content type: Research article Published on:

    The Retraction Note to this article has been published in BMC Physiology 2014 13:13

  2. The frequency of cyanobacterial blooms has increased worldwide, and these blooms have been claimed to be a major factor leading to the decline of the most important freshwater herbivores, i.e. representatives ...

    Authors: Anke Schwarzenberger, Anja Zitt, Peter Kroth, Stefan Mueller and Eric Von Elert
    Citation: BMC Physiology 2010 10:6
    Content type: Research article Published on:

  3. Although identified in several bird species, the biological role of the avian homolog of mammalian uncoupling proteins (avUCP) remains extensively debated. In the present study, the functional properties of is...

    Authors: Benjamin Rey, Damien Roussel, Caroline Romestaing, Maud Belouze, Jean-Louis Rouanet, Dominique Desplanches, Brigitte Sibille, Stéphane Servais and Claude Duchamp
    Citation: BMC Physiology 2010 10:5
    Content type: Research article Published on:

  4. Acylation stimulating protein (ASP) is an adipogenic hormone that stimulates triglyceride (TG) synthesis and glucose transport in adipocytes. Previous studies have shown that ASP-deficient C3 knockout mice are...

    Authors: Sabina Paglialunga, Alexandre Fisette, Mercedes Munkonda, Ying Gao, Denis Richard and Katherine Cianflone
    Citation: BMC Physiology 2010 10:4
    Content type: Research article Published on:

  5. In biomedical sciences, ex vivo angiography is a practical mean to elucidate vascular structures three-dimensionally with simultaneous estimation of intravascular volume. The objectives of this study were to d...

    Authors: Anne S Rasmussen, Henrik Lauridsen, Christoffer Laustsen, Bjarke G Jensen, Steen F Pedersen, Lars Uhrenholt, Lene WT Boel, Niels Uldbjerg, Tobias Wang and Michael Pedersen
    Citation: BMC Physiology 2010 10:3
    Content type: Methodology article Published on:

  6. Laboratory routine procedures such as handling, injection, gavage or transportation are stressful events which may influence physiological parameters of laboratory animals and may interfere with the interpreta...

    Authors: Jakob Olfe, Grazyna Domanska, Christine Schuett and Cornelia Kiank
    Citation: BMC Physiology 2010 10:2
    Content type: Research article Published on:

  7. The low luminal Ca2+ concentration of mammalian endolymph in the inner ear is required for normal hearing and balance. We recently reported the expression of mRNA for a Ca2+-absorptive transport system in primary...

    Authors: Daisuke Yamauchi, Kazuhiro Nakaya, Nithya N Raveendran, Donald G Harbidge, Ruchira Singh, Philine Wangemann and Daniel C Marcus
    Citation: BMC Physiology 2010 10:1
    Content type: Research article Published on:

  8. It has been proposed that adenosine triphosphate (ATP) released from red blood cells (RBCs) may contribute to the tight coupling between blood flow and oxygen demand in contracting skeletal muscle. To determin...

    Authors: Rachel E Wood, Connie Wishart, Philip J Walker, Christopher D Askew and Ian B Stewart
    Citation: BMC Physiology 2009 9:24
    Content type: Research article Published on:

  9. Isoproterenol-induced cardiac hypertrophy in mice has been used in a number of studies to model human cardiac disease. In this study, we compared the transcriptional response of the heart in this model to othe...

    Authors: Cristi L Galindo, Michael A Skinner, Mounir Errami, L Danielle Olson, David A Watson, Jing Li, John F McCormick, Lauren J McIver, Neil M Kumar, Thinh Q Pham and Harold R Garner
    Citation: BMC Physiology 2009 9:23
    Content type: Research article Published on:

  10. Seven-transmembrane receptors typically mediate olfactory signal transduction by coupling to G-proteins. Although insect odorant receptors have seven transmembrane domains like G-protein coupled receptors, the...

    Authors: Abhishek Chatterjee, Gregg Roman and Paul E Hardin
    Citation: BMC Physiology 2009 9:22
    Content type: Research article Published on:

  13. Previous studies of mixed background mice have demonstrated that targeted deletion of Vgf produces a lean, hypermetabolic mouse that is resistant to diet-, lesion-, and genetically-induced obesity. To investigate...

    Authors: Elizabeth Watson, Samira Fargali, Haruka Okamoto, Masato Sadahiro, Ronald E Gordon, Tandra Chakraborty, Mark W Sleeman and Stephen R Salton
    Citation: BMC Physiology 2009 9:19
    Content type: Research article Published on:

  14. Several aquaporins (a family of integral membrane proteins) have been recently identified in the mammalian gastrointestinal tract, and their involvement in the movement of fluid and small solutes has been sugg...

    Authors: Umberto Laforenza, Giulia Gastaldi, Mariarosa Polimeni, Simona Tritto, Marisa Tosco, Ulderico Ventura, Manuela F Scaffino and Masato Yasui
    Citation: BMC Physiology 2009 9:18
    Content type: Research article Published on:

  15. A major endogenous protective mechanism in many organs against ischemia/reperfusion (I/R) injury is ischemic preconditioning (IPC). By moderately uncoupling the mitochondrial respiratory chain and decreasing p...

    Authors: Yajun Liu, Lianbi Chen, Xiaoqun Xu, Eric Vicaut and Richard Sercombe
    Citation: BMC Physiology 2009 9:17
    Content type: Research article Published on:

  16. The cardiomyocyte is a prime example of inherently complex biological system with inter- and cross-connected feedback loops in signalling, forming the basic properties of intracellular homeostasis. Functional ...

    Authors: Jussi T Koivumäki, Topi Korhonen, Jouni Takalo, Matti Weckström and Pasi Tavi
    Citation: BMC Physiology 2009 9:16
    Content type: Research article Published on:

  17. In the mosquito Aedes aegypti the insulin/insulin growth factor I signaling (IIS) cascade is a key regulator of many physiological processes, including reproduction. Two important reproductive events, steroidogen...

    Authors: Anam J Arik, Jason L Rasgon, Kendra M Quicke and Michael A Riehle
    Citation: BMC Physiology 2009 9:15
    Content type: Research article Published on:

  18. Coral bleaching can be defined as the loss of symbiotic zooxanthellae and/or their photosynthetic pigments from their cnidarian host. This major disturbance of reef ecosystems is principally induced by increas...

    Authors: Jeremie Vidal-Dupiol, Mehdi Adjeroud, Emmanuel Roger, Laurent Foure, David Duval, Yves Mone, Christine Ferrier-Pages, Eric Tambutte, Sylvie Tambutte, Didier Zoccola, Denis Allemand and Guillaume Mitta
    Citation: BMC Physiology 2009 9:14
    Content type: Research article Published on:

  19. The objective of this study was to determine if acute heat stress (HS) decreases milk secretion by activating the milk-borne negative feedback system, as an emergency physiological response to prevent a life-t...

    Authors: Nissim Silanikove, Fira Shapiro and Dima Shinder
    Citation: BMC Physiology 2009 9:13
    Content type: Research article Published on:

  20. The stress response is a critical factor in the training of equine athletes; it is important for performance and for protection of the animal against physio-pathological disorders.

    Authors: Katia Cappelli, Michela Felicetti, Stefano Capomaccio, Camillo Pieramati, Maurizio Silvestrelli and Andrea Verini-Supplizi
    Citation: BMC Physiology 2009 9:12
    Content type: Research article Published on:

  22. Our laboratory has shown that a locus on the SHR Y chromosome increases blood pressure (BP) in the SHR rat and in WKY rats with the SHR Y chromosome (SHR/y rat). A candidate for this Y chromosome hypertension ...

    Authors: Daniel Ely, Amy Milsted, Gail Dunphy, Shannon Boehme, Jeff Dunmire, Mike Hart, Jonathon Toot, Almir Martins and Monte Turner
    Citation: BMC Physiology 2009 9:10
    Content type: Research article Published on:

  23. Acidity exerts a determining influence on the composition and diversity of freshwater faunas. While the physiological implications of freshwater acidification have been intensively studied in teleost fish and ...

    Authors: Anna K Weber and Ralph Pirow
    Citation: BMC Physiology 2009 9:9
    Content type: Research article Published on:

  24. Temperature affects essentially every aspect of the biology of poikilothermic animals including the energy and mass budgets, activity, growth, and reproduction. While thermal effects in ecologically important ...

    Authors: Susanne Schwerin, Bettina Zeis, Tobias Lamkemeyer, Rüdiger J Paul, Marita Koch, Johannes Madlung, Claudia Fladerer and Ralph Pirow
    Citation: BMC Physiology 2009 9:8
    Content type: Research article Published on:

  25. Freshwater planktonic crustaceans of the genus Daphnia show a remarkable plasticity to cope with environmental changes in oxygen concentration and temperature. One of the key proteins of adaptive gene control in

    Authors: Bettina Zeis, Tobias Lamkemeyer, Rüdiger J Paul, Frank Nunes, Susanne Schwerin, Marita Koch, Wolfgang Schütz, Johannes Madlung, Claudia Fladerer and Ralph Pirow
    Citation: BMC Physiology 2009 9:7
    Content type: Research article Published on:

  26. Glutathione, the main antioxidant of intestinal epithelial cells, is suggested to play an important role in gut barrier function and prevention of inflammation-related oxidative damage as induced by acute bact...

    Authors: Marleen TJ van Ampting, Arjan J Schonewille, Carolien Vink, Robert Jan Brummer, Roelof vander Meer and Ingeborg MJ Bovee-Oudenhoven
    Citation: BMC Physiology 2009 9:6
    Content type: Research article Published on:

  28. The blood hyperserotonemia of autism is one of the most consistent biological findings in autism research, but its causes remain unclear. A major difficulty in understanding this phenomenon is the lack of info...

    Authors: Ricardo Albay III, Angela Chen, George M Anderson, Maggie Tatevosyan and Skirmantas Janušonis
    Citation: BMC Physiology 2009 9:4
    Content type: Research article Published on:

  29. The aim of the study was to examine the intestinal cellular localization of proliferating cell nuclear antigen (PCNA) and cytochrome P450 A1 (CYP1A) expression in Atlantic salmon Salmo salar L. exposed to a model...

    Authors: Monica Sanden and Pål A Olsvik
    Citation: BMC Physiology 2009 9:3
    Content type: Research article Published on:

  31. Psychophysically, sweet and bitter have long been considered separate taste qualities, evident already to the newborn human. The identification of different receptors for sweet and bitter located on separate c...

    Authors: Yiwen Wang, Vicktoria Danilova, Tiffany Cragin, Thomas W Roberts, Alexey Koposov and Göran Hellekant
    Citation: BMC Physiology 2009 9:1
    Content type: Research article Published on:

  34. There are only few data relating the metabolic consequences of feeding diets very low in n-3 fatty acids. This experiment carried out in mice aims at studying the impact of dietary n-3 polyunsaturated fatty ac...

    Authors: BD Pachikian, AM Neyrinck, PD Cani, L Portois, L Deldicque, FC De Backer, LB Bindels, FM Sohet, WJ Malaisse, M Francaux, YA Carpentier and NM Delzenne
    Citation: BMC Physiology 2008 8:21
    Content type: Research article Published on:

  35. In this study we used radiotelemetry to measure hemodynamic variables and locomotor activity in conscious unrestrained male Protease-Activated Receptor 2 (PAR-2) knockout mice in order to provide a detailed as...

    Authors: John J McGuire, Bruce N Van Vliet and Sarah J Halfyard
    Citation: BMC Physiology 2008 8:20
    Content type: Research article Published on:

  36. Butyrate naturally produced by intestinal fiber fermentation is the main nutrient for colonocytes, but the metabolic effect of the fraction reaching the liver is not totally known. After glycogen hepatic deple...

    Authors: Marie-Christine Beauvieux, Hélène Roumes, Nadège Robert, Henri Gin, Vincent Rigalleau and Jean-Louis Gallis
    Citation: BMC Physiology 2008 8:19
    Content type: Research article Published on:

  37. Insects may use various biochemical pathways to enable them to tolerate the lethal action of insecticides. For example, increased cytochrome P450 detoxification is known to play an important role in many insec...

    Authors: Fang Zhu, Ting Li, Lee Zhang and Nannan Liu
    Citation: BMC Physiology 2008 8:18
    Content type: Research article Published on:

  38. Developmental effects of exposure to endocrine disruptors can influence adult characters in mammals, but could also have evolutionary consequences. The aim of this study was to simulate an environmental exposu...

    Authors: Carlos M Guerrero-Bosagna, Pablo Sabat, Fernanda S Valdovinos, Luis E Valladares and Susan J Clark
    Citation: BMC Physiology 2008 8:17
    Content type: Research article Published on:

  40. To evaluate whether the level of hypotension during hemorrhagic shock may influence the oxidative and inflammatory responses developed during post-ischemic resuscitation.

    Authors: Emmanuel E Douzinas, Ilias Andrianakis, Olga Livaditi, Pantelis Paneris, Marios Tasoulis, Aimilia Pelekanou, Alex Betrosian and Evangelos J Giamarellos-Bourboulis
    Citation: BMC Physiology 2008 8:15
    Content type: Research article Published on:

  41. If European silver eels are prevented from reproductive migration, they remain in a prepubertal stage by dopaminergic inhibition of pituitary activity. Because this inhibition is likely a requirement for an ex...

    Authors: Arjan P Palstra, Denhi Schnabel, Maaike C Nieveen, Herman P Spaink and Guido EEJM van den Thillart
    Citation: BMC Physiology 2008 8:14
    Content type: Research article Published on:

  42. Aldehyde dehydrogenase (ALDH) is a cytosolic enzyme highly expressed in hematopoietic precursors from cord blood and granulocyte-colony stimulating factor mobilized peripheral blood, as well as in bone marrow ...

    Authors: Peppino Mirabelli, Rosa Di Noto, Catia Lo Pardo, Paolo Morabito, Giovanna Abate, Marisa Gorrese, Maddalena Raia, Caterina Pascariello, Giulia Scalia, Marica Gemei, Elisabetta Mariotti and Luigi Del Vecchio
    Citation: BMC Physiology 2008 8:13
    Content type: Research article Published on:

  43. Obesity has been associated with a variety of disease such as type II diabetes mellitus, arterial hypertension and atherosclerosis. Evidences have shown that exercise training promotes beneficial effects on th...

    Authors: Camila de Moraes, Ana Paula Couto Davel, Luciana Venturini Rossoni, Edson Antunes and Angelina Zanesco
    Citation: BMC Physiology 2008 8:12
    Content type: Research article Published on:

  44. Ultradian rhythms, rhythms with a period of less than 24 hours, are a widespread and fundamental aspect of life. The mechanisms underlying the control of such rhythms remain only partially understood. Defecati...

    Authors: Claire SM Kwan, Rafael P Vázquez-Manrique, Sung Ly, Kshamata Goyal and Howard A Baylis
    Citation: BMC Physiology 2008 8:11
    Content type: Research article Published on:

  46. The mechanisms of transmigration of inflammatory cells through the sinusoids are still poorly understood. This study aims to identify in vitro conditions (cytokine treatment) which may allow a better understan...

    Authors: Katrin Neubauer, Alexander Lindhorst, Kyrylo Tron, Giuliano Ramadori and Bernhard Saile
    Citation: BMC Physiology 2008 8:9
    Content type: Research article Published on:

  47. Cardiac insults such as ischemia, infarction, hypertrophy and dilatation are often accompanied by altered abundance and/or localization of the connexin43 gap junction protein, which may predispose towards arrh...

    Authors: Andrianos Kontogeorgis, Riyaz A Kaba, Eunice Kang, Jonathan E Feig, Pritha P Gupta, Marc Ponzio, Fangyu Liu, Michael J Rindler, Andrew L Wit, Edward A Fisher, Nicholas S Peters and David E Gutstein
    Citation: BMC Physiology 2008 8:8
    Content type: Research article Published on:

  49. The function of voltage-gated calcium (Cav) channels greatly depends on coupling to cytoplasmic accessory β subunits, which not only promote surface expression, but also modulate gating and kinetic properties of ...

    Authors: Vicenta Salvador-Recatalà, Toni Schneider and Robert M Greenberg
    Citation: BMC Physiology 2008 8:6
    Content type: Research article Published on:

  50. The Y-chromosome (Yc) and testosterone (T) increase blood pressure and may also influence renal electrolyte excretion. Therefore, the goal of this study was to determine if the Yc combined with T manipulation ...

    Authors: Jonathan Toot, Cathy Jenkins, Gail Dunphy, Shannon Boehme, Mike Hart, Amy Milsted, Monte Turner and Daniel Ely
    Citation: BMC Physiology 2008 8:5
    Content type: Research article Published on:

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