Metabolism and homeostasis

This section aims to publish studies concerned with the physiological understanding of the regulation of metabolism and its dysfunction in disease and the dynamic physiological processes that enable optimum conditions to be maintained for cells, tissues and whole organisms.

  1. Research article

    Alteration in circulating metabolites during and after heat stress in the conscious rat: potential biomarkers of exposure and organ-specific injury

    Heat illness is a debilitating and potentially life-threatening condition. Limited data are available to identify individuals with heat illness at greatest risk for organ damage. We recently described the tran...

    Danielle L Ippolito, John A Lewis, Chenggang Yu, Lisa R Leon and Jonathan D Stallings

    BMC Physiology 2014 14:14

    Published on: 24 December 2014

  2. Research article

    White-nose syndrome initiates a cascade of physiologic disturbances in the hibernating bat host

    The physiological effects of white-nose syndrome (WNS) in hibernating bats and ultimate causes of mortality from infection with Pseudogymnoascus (formerly Geomyces) destructans are not fully understood. Increased...

    Michelle L Verant, Carol U Meteyer, John R Speakman, Paul M Cryan, Jeffrey M Lorch and David S Blehert

    BMC Physiology 2014 14:10

    Published on: 9 December 2014

  3. Research article

    Quinine controls body weight gain without affecting food intake in male C57BL6 mice

    Quinine is a natural molecule commonly used as a flavouring agent in tonic water. Diet supplementation with quinine leads to decreased body weight and food intake in rats. Quinine is an in vitro inhibitor of Trpm...

    Philippe Cettour-Rose, Carole Bezençon, Christian Darimont, Johannes le Coutre and Sami Damak

    BMC Physiology 2013 13:5

    Published on: 8 February 2013

  4. Research article

    Localization of lipoprotein lipase and GPIHBP1 in mouse pancreas: effects of diet and leptin deficiency

    Lipoprotein lipase (LPL) hydrolyzes triglycerides in plasma lipoproteins and enables uptake of lipolysis products for energy production or storage in tissues. Our aim was to study the localization of LPL and i...

    Rakel Nyrén, Chuchun L Chang, Per Lindström, Anastasia Barmina, Evelina Vorrsjö, Yusuf Ali, Lisa Juntti-Berggren, André Bensadoun, Stephen G Young, Thomas Olivecrona and Gunilla Olivecrona

    BMC Physiology 2012 12:14

    Published on: 27 November 2012

  5. Research article

    Linking nutritional regulation of Angptl4, Gpihbp1, and Lmf1 to lipoprotein lipase activity in rodent adipose tissue

    Lipoprotein lipase (LPL) hydrolyzes triglycerides in lipoproteins and makes fatty acids available for tissue metabolism. The activity of the enzyme is modulated in a tissue specific manner by interaction with ...

    Olessia Kroupa, Evelina Vorrsjö, Rinke Stienstra, Frits Mattijssen, Stefan K Nilsson, Valentina Sukonina, Sander Kersten, Gunilla Olivecrona and Thomas Olivecrona

    BMC Physiology 2012 12:13

    Published on: 23 November 2012