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BMC Physiology

Circulation, cardiovascular and respiratory physiology

This section aims to publish studies on the regulation, function and activities of the cardiovascular and respiratory systems, respiratory mechanics as well as disturbances and adaptations of these systems in disease states.

  1. Content type: Research article

    Reports on the effect of age and obesity on myocardial ischaemia/reperfusion (I/R) injury and ischaemic preconditioning are contradictory. The aim of this study was to re-evaluate the effects of age and diet-i...

    Authors: I. Webster, R. Salie, E. Marais, W.-J. Fan, G. Maarman, B. Huisamen and A. Lochner

    Citation: BMC Physiology 2017 17:3

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  2. Content type: Research article

    In many vascular smooth muscle cells (SMCs), ryanodine receptor-mediated Ca2+ sparks activate large-conductance Ca2+-activated K+ (BK) channels leading to lowered SMC [Ca2+]i and vasodilation. Here we investigate...

    Authors: Gayathri Krishnamoorthy, Katrin Reimann and Philine Wangemann

    Citation: BMC Physiology 2016 16:6

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  3. Content type: Research article

    In vitro isolated heart preparations are valuable tools for the study of cardiac anatomy and physiology, as well as for preclinical device testing. Such preparations afford investigators a high level of hemody...

    Authors: Ryan P. Goff, Brian T. Howard, Stephen G. Quallich, Tinen L. Iles and Paul A. Iaizzo

    Citation: BMC Physiology 2016 16:4

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  1. Content type: Research article

    Veterinary cardiology, especially electrocardiography, has shown major advancements for all animal species. Consequently, the number of ovine species used as experimental animals has increased to date. Few stu...

    Authors: Karoline Koether, Carla Maria Vela Ulian, Maria Lucia Gomes Lourenço, Renato Souza Gonçalves, Mateus José Sudano, Raíssa Karolliny Salgueiro Cruz, Naiana da Silva Branchini, Angélica Alfonso and Simone Biagio Chiacchio

    Citation: BMC Physiology 2016 16:1

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  2. Content type: Research article

    There is a close relationship between cardiovascular disease and cardiac energy metabolism, and we have previously demonstrated that palmitate inhibits myocyte contraction by increasing Kv channel activity and de...

    Authors: James F Schooley, Aryan MA Namboodiri, Rachel T Cox, Rolf Bünger and Thomas P Flagg

    Citation: BMC Physiology 2014 14:12

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  3. Content type: Research article

    MAPK-activated protein kinase 2 (MK2) plays a pivotal role in the cell response to (inflammatory) stress. Among others, MK2 is known to be involved in the regulation of cytokine mRNA metabolism and regulation ...

    Authors: Benjamin Vandendriessche, An Goethals, Alba Simats, Evelien Van Hamme, Peter Brouckaert and Anje Cauwels

    Citation: BMC Physiology 2014 14:5

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  4. Content type: Research article

    Dysregulation of the autonomic nervous system is frequent in subjects with cardiovascular disease. The contribution of different forms of renovascular hypertension and the mechanisms contributing to autonomic ...

    Authors: Rainer U Pliquett, Sebastian Benkhoff, Oliver Jung and Ralf P Brandes

    Citation: BMC Physiology 2014 14:4

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  5. Content type: Research article

    Postprandial lipidemia is important in the development of coronary artery disease (CAD). Consumption of a meal high in monounsaturated fat was correlated with acute impairment of endothelial function. However,...

    Authors: Ping Yi, Jia Pang, Jonathan Steven Alexander and Chantal Rivera

    Citation: BMC Physiology 2013 13:12

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  6. Content type: Research article

    ATP-sensitive K+ channels (KATP channels), NO, prostaglandins, 20-HETE and L-type Ca2+ channels have all been suggested to be involved in oxygen sensing in skeletal muscle arterioles, but the role of the individu...

    Authors: AnhThuc Ngo, Mads Riemann, Niels-Henrik Holstein-Rathlou, Christian Torp-Pedersen and LarsJørn Jensen

    Citation: BMC Physiology 2013 13:8

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