Circulation, cardiovascular and respiratory physiology

This section aims to publish studies on the regulation, function and activities of the cardiovascular and respiratory systems, respiratory mechanics as well as disturbances and adaptations of these systems in disease states.

  1. Research article

    Ryanodine-induced vasoconstriction of the gerbil spiral modiolar artery depends on the Ca2+ sensitivity but not on Ca2+ sparks or BK channels

    In many vascular smooth muscle cells (SMCs), ryanodine receptor-mediated Ca2+ sparks activate large-conductance Ca2+-activated K+ (BK) channels leading to lowered SMC [Ca2+]i and vasodilation. Here we investigate...

    Gayathri Krishnamoorthy, Katrin Reimann and Philine Wangemann

    BMC Physiology 2016 16:6

    Published on: 2 November 2016

  1. Research article

    The normal electrocardiograms in the conscious newborn lambs in neonatal period and its progression

    Veterinary cardiology, especially electrocardiography, has shown major advancements for all animal species. Consequently, the number of ovine species used as experimental animals has increased to date. Few stu...

    Karoline Koether, Carla Maria Vela Ulian, Maria Lucia Gomes Lourenço, Renato Souza Gonçalves, Mateus José Sudano, Raíssa Karolliny Salgueiro Cruz, Naiana da Silva Branchini, Angélica Alfonso and Simone Biagio Chiacchio

    BMC Physiology 2016 16:1

    Published on: 19 January 2016

  2. Research article

    MAPK-activated protein kinase 2-deficiency causes hyperacute tumor necrosis factor-induced inflammatory shock

    MAPK-activated protein kinase 2 (MK2) plays a pivotal role in the cell response to (inflammatory) stress. Among others, MK2 is known to be involved in the regulation of cytokine mRNA metabolism and regulation ...

    Benjamin Vandendriessche, An Goethals, Alba Simats, Evelien Van Hamme, Peter Brouckaert and Anje Cauwels

    BMC Physiology 2014 14:5

    Published on: 4 September 2014

  3. Research article

    Significance of KATP channels, L-type Ca2+ channels and CYP450-4A enzymes in oxygen sensing in mouse cremaster muscle arterioles In vivo

    ATP-sensitive K+ channels (KATP channels), NO, prostaglandins, 20-HETE and L-type Ca2+ channels have all been suggested to be involved in oxygen sensing in skeletal muscle arterioles, but the role of the individu...

    AnhThuc Ngo, Mads Riemann, Niels-Henrik Holstein-Rathlou, Christian Torp-Pedersen and LarsJørn Jensen

    BMC Physiology 2013 13:8

    Published on: 12 May 2013